PAPER PRESENTATION IN TSAPICON ( 2022 )

 Presentation link : https://youtu.be/ORUPNrUwyJ4


TITLE :EVALUATION OF SERUM LIPID PROFILE IN STROKE PATIENTS 

INTRODUCTION:

1)Stroke is an important cause of disability among adults and is one of the leading causes of death worldwide.

2) A stroke, or cerebrovascular accident, is defined by the abrupt onset of a neurologic deficit that is attributable to a focal vascular cause.

3)It is important to evaluate the serum lipid levels in both the types of strokes to guide lipid lowering therapy which can reduce incidence of stroke and related mortality .

AIM AND OBJECTIVE:

To study the serum lipid profile in stroke patients

MATERIAL AND METHODS:

This is a prospective observational study conducted at Kamineni institute of medical sciences,Narketpally from August 2020 to August 2022.This study involved 50 patients of stroke cases .

INCLUSION CRITERIA:

 Age more than 18 years 

Patient with acute stroke 

EXCLUSION CRITERIA:

Patients with head injury, primary or secondary brain tumor were excluded from the study 

RESULTS:

1)Increased total cholesterol seen in 35.71 % of ischemic cases and 25% of haemorrhagic cases

2)Decreased HDL found in 52.38% of ischemic cases and 37.5% of haemorrhagic cases.  


DISCUSSION:

1)Dyslipidemia is a primary major risk factor for ischemic stroke. 

2)It causes insulin resistance which results in increased levels of plasma triglycerides and low-density lipoprotein cholesterol (LDL-C) and a decreased concentration of HDL-C, as an important risk factor for stroke.

 3)NCEP-III guidelines suggest that all patients at risk for stroke or who have had a cerebral infarction should be treated to a goal LDL level of below 70 mg/dL. 

 CONCLUSION:

Regular monitor of lipid profile among stroke patients may decrease the risk of atherosclerosis and cardiovascular disease among the stroke patients.

REFERENCES:

1)Bonita R, Mendis S, Truelsen T, Bogousslavsky J, Toole J, Yatsu F. The global stroke initiative. Lancet Neurol. 2004;3:391-3.

2)Kirshner HS. Medical prevention of stroke. South Med J. 2003;96:354-8 

3)Grundy, Sacco, Anthony S. Kim N, S. Claiborne Johnston. Neurologic complications of hypertension. In: Grundy, Sacco, Anthony S. Kim N, S. Claiborne Johnston, eds. Aminoff’s Neurology and General Medicine. 2nd ed. USA: Academic Press; 1996 and 2004:1216.

4)Wild SH, Byrne CD, Tzoulaki I, Lee AJ, Rumley A, Lowe GD, et al. Metabolic syndrome, haemostatic and inflammatory markers, cerebrovascular and peripheral arterial disease. Edinburgh Artery Study. Atherosclerosis. 2009;203:604-9.

5)Sacco RL. Risk factors and outcomes for ischemic stroke. Neurol. 1995;45:S10ischemic stroke. Neurol. 1995;45:S10

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